The project aims to serve the national interest by providing opportunities for hands-on laboratory research for two-year college students that strengthen STEM competencies, build academic confidence, and develop workforce-ready skills. Miami Dade College aims to launch technology-rich, course-based undergraduate research experiences (CUREs) that engage students in cutting-edge biological research. Over a three-year period, students explore the intersection of artificial intelligence, machine learning, and retrovirology while investigating methods to disrupt the life cycle of HIV. Through a combination of hands-on laboratory work, digital modeling, and professional mentorship, participants gain valuable experience that supports advancement in STEM academic pathways and careers. These research experiences are embedded within existing dual enrollment and associate degree programs, allowing students to earn college credit while participating in meaningful real-world research. The project promotes innovation in education, strengthens STEM pathways at two-year colleges, and contributes to cultivating the next generation of scientists. Project goals are to: (1) facilitate undergraduate research opportunities in biomedical AI-driven research, and (2) advance undergraduate STEM education by strengthening transfer pathways to four-year institutions and STEM careers. To achieve these goals, the project provides dual enrollment and two-year college students with structured research