I-Corps: Translation Potential of Three-dimensional Printable Modular Flow Reactors

NSF Award Search · 01002526DB NSF RESEARCH & RELATED ACTIVIT · $50,000 · view on nsf.gov ↗

Abstract

This I-Corps project investigates the commercial potential of a modular, low-cost, flow reactor system that enables chemical reactions to be performed more safely, efficiently, and affordably. The system, which features components that can be manufactured using three-dimensional printing, addresses a critical market need for affordable and customizable chemical synthesis tools, particularly for small to mid-sized companies. Traditional flow reactors are often prohibitively expensive and designed for large-scale operations, leaving early-stage pharmaceutical and specialty chemical companies without viable, affordable options. This innovation aims to reduce financial and technical barriers to continuous flow chemistry, a process known for improving safety and reproducibility in laboratory settings. By making sophisticated chemical processing equipment more accessible, the project supports national interests in economic competitiveness, scientific advancement, and public health through safer laboratory practices and more efficient chemical manufacturing of chemical building blocks and materials for the pharmaceutical, agrochemical and organic electronics industries. This I-Corps project utilizes experiential learning coupled with a first-hand investigation of the industry ecosystem to assess the translation potential of the technology. This solution is based on the development of a customizable photochemical flow reactor built using three-dimensional printing techniques, all

Key facts

NSF award ID
2533763
Awardee
Colorado State University (CO)
SAM.gov UEI
LT9CXX8L19G1
PI
Olga V Boltalina
Primary program
01002526DB NSF RESEARCH & RELATED ACTIVIT
All programs
Chemical Technology
Estimated total
$50,000
Funds obligated
$50,000
Transaction type
Standard Grant
Period
09/15/2025 → 08/31/2026