This I-Corps project is based on the development of supercomputers for real-time, interactive problem solving and data analysis. Currently, there are significant problems in creating robust, complex, open-ended learning environments that are personalized, engaging, adaptive and scalable. Yet, such environments have great potential for the development of valuable real-world skills (e.g., creativity, leadership, and collaboration). Preliminary implementations of this type of technology exist in medical simulation and military training, and it is emerging in K-12 and higher education. In addition, supercomputers are used in on-the-job training and life-long learning experiences. This technology addresses the challenges by providing well-integrated, immersive, collaborative, and virtual/physical extended reality environments. These environments provide unparalleled tools for research collaborations, intellectual exploration, education, and creative output. They incorporate visual, audio, and physical components; artificial intelligence (AI) technologies to enhance human-human, human-agent, and human-robot social interactions; rapid prototyping and fabrication tools; and tightly coupled interactive visual, audio, and physical experiences. This solution may be applied to next-generation healthcare simulators, advanced cyberlearning environments, and smart homes for well-being and entertainment. The technology provides deep integration of virtual and physical settings and has the po