I-Corps: Translation potential of a bioelectronic platform to diagnose and treat muscle wasting disorders

NSF Award Search · 01002526DB NSF RESEARCH & RELATED ACTIVIT · $50,000 · view on nsf.gov ↗

Abstract

This I-Corps project is based on the development of a medical device designed to diagnose and treat muscle-wasting disorders. Muscle-wasting disorders affect millions of individuals globally, leading to decreased quality of life, loss of mobility, and increased healthcare costs. These disorders can result from aging, chronic diseases, traumatic injuries, or prolonged inactivity. Current solutions primarily focus on symptom management rather than addressing the underlying loss of muscle function and structure. This technology is based on electrical stimulation combined with diagnostic capabilities to effectively restore muscle health and functionality. Directly addressing muscle degeneration and promoting muscle regeneration may improve patient outcomes and quality of life. In addition, this device may reduce healthcare costs by providing an effective alternative to existing treatments, while enhancing patient independence. This I-Corps project utilizes experiential learning coupled with a first-hand investigation of the industry ecosystem to assess the translation potential of an advanced bioelectronic platform employing integrated therapeutic stimulation and diagnostic monitoring technologies. The core technology is based on a customizable, wearable bioelectronic interface capable of delivering targeted neuromuscular electrical stimulation to promote muscle regeneration and strength recovery. Unlike existing therapies, this technology uniquely incorporates real-time diagn

Key facts

NSF award ID
2536056
Awardee
Carnegie Mellon University (PA)
SAM.gov UEI
U3NKNFLNQ613
PI
Tzahi Cohen-Karni
Primary program
01002526DB NSF RESEARCH & RELATED ACTIVIT
All programs
BIOMEDICAL ENGINEERING
Estimated total
$50,000
Funds obligated
$50,000
Transaction type
Standard Grant
Period
09/15/2025 → 08/31/2026