Testing the Addition of Radiation Therapy to the Usual Treatment (Immunotherapy With or Without Chemotherapy) for Advanced Stage Non-small Cell Lung Cancer Patients Who Are PD-L1 Negative

NCT04929041 · clinicaltrials.gov ↗

PHASE2,PHASE3

Phase

SUSPENDED

Status

427

Enrollment

NIH

Sponsor class

Stopped End of Initial Phase of Multi-phase protocol

Conditions

Lung Adenocarcinoma
Lung Adenosquamous Carcinoma
Lung Non-Small Cell Carcinoma
Stage IIIB Lung Cancer AJCC v8
Stage IIIC Lung Cancer AJCC v8
Stage IV Lung Cancer AJCC v8

Interventions

PROCEDURE: Biopsy Procedure
PROCEDURE: Biospecimen Collection
PROCEDURE: Computed Tomography
PROCEDURE: Echocardiography Test
BIOLOGICAL: Ipilimumab
PROCEDURE: Magnetic Resonance Imaging
BIOLOGICAL: Nivolumab
PROCEDURE: Positron Emission Tomography
OTHER: Quality-of-Life Assessment
RADIATION: Radiation Therapy

Sponsor

National Cancer Institute (NCI)