Autologous Tumor Infiltrating Lymphocytes With Interleukin-2 for the Treatment of Locally Advanced, Recurrent or Metastatic Gastrointestinal Stromal Tumors

NCT07647068 · clinicaltrials.gov ↗

PHASE2

Phase

NOT_YET_RECRUITING

Status

59

Enrollment

OTHER

Sponsor class

Conditions

Locally Advanced Gastrointestinal Stromal Tumor
Metastatic Gastrointestinal Stromal Tumor
Recurrent Gastrointestinal Stromal Tumor
Refractory Malignant Gastrointestinal Stromal Tumor
Unresectable Malignant Gastrointestinal Stromal Tumor

Interventions

BIOLOGICAL: Aldesleukin
PROCEDURE: Biospecimen Collection
PROCEDURE: Chest Radiography
PROCEDURE: Computed Tomography
DRUG: Cyclophosphamide
PROCEDURE: Echocardiography Test
BIOLOGICAL: Filgrastim
DRUG: Fludarabine
PROCEDURE: Magnetic Resonance Imaging
PROCEDURE: Multigated Acquisition Scan
PROCEDURE: Positron Emission Tomography
PROCEDURE: Surgical Procedure
BIOLOGICAL: Tumor Infiltrating Lymphocyte Therapy

Sponsor

Joal Beane