Lymphodepletion With Low Dose Total Body Irradiation Before Standard of Care Tisagenlecleucel for the Treatment of Relapsed and Recurrent Large B-cell Lymphoma

NCT07676877 · clinicaltrials.gov ↗

PHASE1

Phase

RECRUITING

Status

18

Enrollment

OTHER

Sponsor class

Conditions

Recurrent Diffuse Large B-Cell Lymphoma
Refractory Diffuse Large B-Cell Lymphoma

Interventions

PROCEDURE: Biospecimen Collection
PROCEDURE: Computed Tomography
DRUG: Cyclophosphamide
DRUG: Fludarabine
PROCEDURE: Leukapheresis
PROCEDURE: Positron Emission Tomography
BIOLOGICAL: Tisagenlecleucel
RADIATION: Total-Body Irradiation

Sponsor

Nathan Denlinger

Collaborators

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