Epcoritamab and Pola-R-mini-CHP for the Treatment of Diffuse Large B Cell Lymphoma in Elderly or Unfit Patients

NCT07714421 · clinicaltrials.gov ↗

PHASE1

Phase

NOT_YET_RECRUITING

Status

20

Enrollment

OTHER

Sponsor class

Conditions

Diffuse Large B-Cell Lymphoma
Grade 3b Follicular Lymphoma
High Grade B-Cell Lymphoma
Primary Mediastinal Large B-Cell Lymphoma
Transformed Marginal Zone Lymphoma to Diffuse Large B-Cell Lymphoma

Interventions

PROCEDURE: Biospecimen Collection
PROCEDURE: Computed Tomography
DRUG: Cyclophosphamide
DRUG: Doxorubicin
BIOLOGICAL: Epcoritamab
PROCEDURE: Magnetic Resonance Imaging
DRUG: Polatuzumab Vedotin
PROCEDURE: Positron Emission Tomography
DRUG: Prednisone
BIOLOGICAL: Rituximab

Sponsor

Jonsson Comprehensive Cancer Center

Collaborators

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