Exploration of Appropriate BIS Range and Propofol Effect-site Concentration During Total Intravenous Anesthesia With Concomitant Adjuvants.
Conditions
- Knee Osteoarthritis
- Replacement, Knee
- Elective Surgical Patients
- ASA Class I/II Patients
Interventions
- DRUG: Propofol + Remifentanil +Midazolam
- DRUG: Propofol + Remifentanil + Dexmedetomidine
- DRUG: Propofol + Remifentanil + Esketamine
- DRUG: Propofol + Remifentanil
Sponsor
China-Japan Friendship Hospital