DYSPHAGIA IN ALZHEIMER'S DISEASE

NIH RePORTER · NIH · R01 · $90,532 · view on reporter.nih.gov ↗

Abstract

Non-cognitive symptoms of Alzheimer's disease (AD) include feeding abnormalities, and aspiration pneumonia. Though dysphagia is generally recognized to be a major contributor to morbidity in Alzheimer's dementia, information about this disorder is lacking. Therefore, the objective of this investigation is to examine the frequency and progression of dysphagia in patients with AD. Dysphagia severity (defined in this study as oropharyngeal aspiration or risk for aspiration), will be described using a videofluoroscopic modified barium swallow technique. The swallowing examination will occur at the patient's entry into the study, and 12 months later. Dysphagia severity will be correlated with cognitive status, eating dependency, physical examination, head CT or head MRI abnormalities, and the occurrence or re-occurrence of aspiration pneumonia.

Key facts

NIH application ID
3122578
Project number
5R01AG010648-02
Recipient
DUKE UNIVERSITY
SAM.gov UEI
TP7EK8DZV6N5
Principal Investigator
Jennifer Horner
Activity code
R01
Funding institute
NIH
Fiscal year
1992
Award amount
$90,532
Award type
5
Project period
1991-09-30 → 1994-03-31